Tenuigenin
Cat. No.：YN410120
| 产品名称: | Tenuigenin |
| CAS No.: | 2469-34-3 |
| Chemical Name: | (2β,3β,4α,12α)-12-(chloromethyl)-2,3-dihydroxy-27-norolean-13-ene-23,28-dioic acid |
| Synonyms: | 远志皂苷元; Senegenin |
| 分子量: | 537.13 |
| 分子式: | C₃₀H₄₅ClO₆ |
| SMILES: | C[C@@]([C@](CC1)([H])[C@]2(C)C(O)=O)(C[C@H](O)[C@@H]2O)[C@](C[C@H](CCl)C3=C4CC[C@]5(C(O)=O)[C@@]3([H])CC(C)(C)CC5)([H])[C@]41C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tenuigenin 是从中草药远志 (Polygala tenuifolia) 根中分离出来的主要活性成分。Tenuigenin 通过抑制NF-κB活化来预防金黄色葡萄球菌诱导的肺炎。 |
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Dugan, J.J., De Mayo, P., and Starratt, A.N.Terpenoids: V. Senegenin: Functional groups and part structureCan. J. Chem.42(3),491-501(1964)
Fan, Z., Liang, Z., Yang, H., et al.Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microgliaJ. Neuroinflammation14(1),256(2017)
Yu, B., Qiao, J., Shen, Y., et al.Protective effects of tenuigenin on Staphylococcus aureus-induced pneumonia in miceMicrob. Pathog.110,385-389(2017)
