Rubiadin-1-methyl ether
Cat. No.：YN410128
| 产品名称: | Rubiadin-1-methyl ether |
| CAS No.: | 7460-43-7 |
| Chemical Name: | 3-hydroxy-1-methoxy-2-methyl-9,10-anthracenedione |
| Synonyms: | Rubiadin 1-methyl ether,3-羟基-1-甲氧基-2-甲基蒽醌 |
| 分子量: | 268.26 |
| 分子式: | C₁₆H₁₂O₄ |
| SMILES: | O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(C)C(OC)=C13)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rubiadin-1-methyl ether 是巴戟天中的蒽醌类化合物，可抑制破骨细胞性骨吸收，通过抑制NF-κB p65磷酸化水平，降解 IκBα 蛋白，以及降低 p65 的核转位起作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Montoya, S.C.N., Comini, L.R., Sarmiento, M., et al.Natural anthraquinones probed as Type I and Type II photosensitizers: Singlet oxygen and superoxide anion productionJ. Photochem. Photobiol. B.78(1),77-83(2005)
He, Y.-Q., Zhang, Q., Shen, Y., et al.Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathwayBiochem. Biophys. Res. Commun.506(4),927-931(2018)
Marioni, J., da Silva, M.A., Cabrera, J.L., et al.The anthraquinones rubiadin and its 1-methyl ether isolated from Heterophyllaea pustulata reduces Candida tropicalis biofilms formationPhytomedicine23(12),1321-1328(2016)
Mohr, E.T.B., Nascimento, M.V.P.D.S., da Rosa, J.S., et al.Evidence that the anti-inflammatory effect of rubiadin-1-methyl ether has an immunomodulatory contextMediators Inflamm.,6474168(2019)
