Praeruptorin A
Cat. No.:YN410142
产品名称: | Praeruptorin A |
CAS No.: | 73069-27-9 |
Chemical Name: | (2Z)-2-methyl-2-butenoic acid, (9S,10S)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester |
Synonyms: | 白花前胡甲素 |
分子量: | 386.40 |
分子式: | C₂₁H₂₂O₇ |
SMILES: | CC(O[C@H]1C2=C(OC(C)(C)[C@H]1OC(/C(C)=C\C)=O)C=CC(C=C3)=C2OC3=O)=O.[S].[S] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Praeruptorin A 是白花前胡 (Peucedanum praeruptorum) 的一种主要生物活性成分。Praeruptorin A 通过抑制NF-κB活化而发挥抗炎作用。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Zheng-Xiong, G., Huang, B.-S., She, Q.-L., et al.Study on the chemical constituents of the Chinese medicinal plant, Peucedanum praeruptorum Dunn. Structures of four new coumarinsYaoxue Xuebao14(8),486-496(1979)
Lee, J., Lee, Y.J., Kim, J., et al.Pyranocoumarins from root extracts of Peucedanum praeruptorum Dunn with multidrug resistance reversal and anti-inflammatory activitiesMolecules20(12),20967-20978(2015)
Zhao, N.C., Jin, W.B., Zhang, X.H., et al.Relaxant effects of pyranocoumarin compounds isolated from a Chinese medical plant, Bai-Hua Qian-Hu, on isolated rabbit tracheas and pulmonary arteriesBiol. Pharm. Bull.22(9),984-987(1999)
Menghini, L., Epifano, F., Genovese, S., et al.Antiinflammatory activity of coumarins from Ligusticum lucidum Mill. subsp. cuneifolium (Guss.) Tammaro (Apiaceae)Phytother. Res.24(11),1697-1699(2010)