4-O-Methyl honokiol
Cat. No.：YN410153
CAS No. ：68592-15-4
| 产品名称: | 4-O-Methyl honokiol |
| CAS No.: | 68592-15-4 |
| Chemical Name: | 4′-methoxy-3′,5-di-2-propen-1-yl-[1,1′-biphenyl]-2-ol |
| Synonyms: | 4--O-甲基和厚朴酚 |
| 分子量: | 280.36 |
| 分子式: | C₁₉H₂₀O₂ |
| SMILES: | OC1=CC=C(CC=C)C=C1C2=CC=C(OC)C(CC=C)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4-O-Methyl honokiol 是从厚朴中分离到的木脂素类化合物，为PPARγ的激动剂，可抑制NF-κB的活性，用于癌症，炎症等研究。 |
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Clark, A.M., El-Feraly, F.S., and Li, W.S.Antimicrobial activity of phenolic constituents of Magnolia grandiflora LJ. Pharm. Sci.70(8),951-952(1981)
Zhou, H.Y., Shin, E.M., Guo, L.Y., et al.Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB, JNK and p38 MAPK inactivationEur. J. Pharmacol.586(1-3),340-349(2008)
Lee, J.W., Lee, Y.K., Lee, B.J., et al.Inhibitory effect of ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on memory impairment and neuronal toxicity induced by beta-amyloidPharmacol. Biochem. Behav.95(1),31-40(2010)
Zhang, Z., Chen, J., Jiang, X., et al.The magnolia bioactive constituent 4-O-methylhonokiol protects against high-fat diet-induced obesity and systemic insulin resistance in miceOxid. Med. Cell. Longev.2014,965954(2014)
