Chelidonic acid
Cat. No.：YN410155
| 产品名称: | Chelidonic acid |
| CAS No.: | 99-32-1 |
| Chemical Name: | 4-oxo-4H-pyran-2,6-dicarboxylic acid |
| Synonyms: | 白屈菜酸 |
| 分子量: | 184.10 |
| 分子式: | C₇H₄O₆ |
| SMILES: | O=C(C1=CC(C=C(C(O)=O)O1)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chelidonic acid 是从Chelidonium majus L.中分到的酸类物质，为一种温和镇痛剂、抗菌剂和中枢神经系统镇静剂。Chelidonic acid 具有抗炎作用，可能通过抑制NF-κB和caspase-1来降低 IL-6 的产生。Chelidonic acid 为glutamate decarboxylase抑制剂，Ki值为 1.2 μM。 |
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Kim, D.-S., Kim, S.-J., Kim, M.-C., et al.The therapeutic effect of chelidonic acid on ulcerative colitisBiol. Pharm. Bull.35(5),666-671(2012)
Porter, T.G., and Martin, C.L.Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylaseBiochem. Pharmacol.34(23),4145-4150(1985)
Oh, H.-A., Kim, H.-M., and Jeong, H.-J.Beneficial effects of chelidonic acid on a model of allergic rhinitisInt. Immunopharmacol.11(1),39-45(2011)
