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> 产品中心 > 抑制剂 & 激动剂 > Membrane Transporter/Ion Chann > Na+/K+ ATPase

Marinobufogenin

Cat. No.:YN360995

  • CAS No. :470-42-8

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    • 生物活性
    • 参考文献
    • 产品名称: Marinobufogenin
      CAS No.: 470-42-8
      Chemical Name: (3β,5β,15β)-14,15-epoxy-3,5-dihydroxy-bufa-20,22-dienolide
      Synonyms:南美蟾毒精,Marinobufagenin
      分子量:400.51
      分子式:C₂₄H₃₂O₅
      SMILES:C[C@@]12[C@]3([C@H](O3)C[C@@H]2C(C=C4)=COC4=O)[C@]5([C@]([H])(CC1)[C@]6(C)[C@@](C[C@H](CC6)O)(CC5)O)[H]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Marinobufogenin 是Na+/K+ATPase的高效抑制剂,最初从哺乳动物血浆中鉴定得到。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Fedorova, O.V., Kolodkin, N.I., Agalakova, N.I., et al.Marinobufagenin, an endogenous alpha-1 sodium pump ligand, in hypertensive Dahl salt-sensitive ratsHypertension37(2 Pt 2),462-466(2001)

      Schoner, W., and Scheiner-Bobis, G.Role of endogenous cardiotonic steroids in sodium homeostasisNephrol. Dial. Transplant.23(9),2723-2729(2008)

      Schoner, W.Endogenous cardiac glycosides, a new class of steroid hormonesEur. J. Biochem.269(10),2440-2448(2002)

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