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Citreoviridin

Cat. No.:YN361001

  • CAS No. :25425-12-1

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    • 生物活性
    • 参考文献
    • 产品名称: Citreoviridin
      CAS No.: 25425-12-1
      Chemical Name: 2,5-anhydro-1,6-dideoxy-2-C-[(8-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-2-methyl-1E,3E,5E,7E-octatetraen-1-yl]-4-C-methyl-D-iditol
      Synonyms:
      分子量:402.48
      分子式:C₂₃H₃₀O₆
      SMILES:CC(/C=C/C=C/C=C/C(O1)=C(C(OC)=CC1=O)C)=C\[C@]2([C@H](O)[C@]([C@H](O2)C)(O)C)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Citreoviridin 是一种来自Penicillium citreovirideNRRL 2579 的毒素,抑制脑突触体Na+/K+ATPase,而在微粒体中,刺激Na+/K+-ATPase和 Mg2+-ATPase 活性。Citreoviridin 作用于人脐静脉内皮细胞,抑制细胞增殖并促进凋亡 (apoptosis)。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Linnett, P.E., Mitchell, A.D., Osselton, M.D., et al.Citreoviridin, a specific inhibitor of the mitochondiral adenosine triphosphataseBiochem. J.170(3),503-510(1978)

      Gause, E.M., Buck, M.A., and Douglas, M.G.Binding of citreoviridin to the β subunit of the yeast F1-ATPaseJ. Biol. Chem.256(2),557-559(1981)

      Wu, Y.H., Hu, C.W., Chien, C.W., et al.Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridinPLoS One8(8),1-19(2013)

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