BP 897
Cat. No.：YN1730023
CAS No. ：314776-92-6
| 产品名称: | BP 897 |
| CAS No.: | 314776-92-6 |
| Chemical Name: | N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-2-naphthalenecarboxamide, monohydrochloride |
| Synonyms: | 2-Naphthalenecarboxamide,N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-, hydrochloride (1:1);BP897;N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-2-naphthamide hydr ochloride (1:1);N-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-2-naphthamide hydrochlorid |
| 分子量: | 454.00 |
| 分子式: | C₂₆H₃₂ClN₃O₂ |
| SMILES: | COC1=C(N2CCN(CCCCNC(C3=CC4=C(C=CC=C4)C=C3)=O)CC2)C=CC=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BP 897 是一种有效的，选择性的多巴胺 D3 受体 (dopamine D3 receptor) 部分激动剂，为较弱的多巴胺 D2 受体 (dopamine D2 receptor) 拮抗剂，Ki值分别为 0.92 nM 和 61 nM，对 D1 和 D4 受体的亲和性较低，Ki值分别为 3 和 0.3 µM。 |
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Pilla, M., Perachon, S., Sautel, F., et al.Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonistNature400(6742),371-375(1999)
Wicke, K., and Garcia-Ladona, J.The dopamine D3 receptor partial agonist, BP 897, is an antagonist at human dopamine D3 receptors and at rat somatodendritic dopamine D3 receptorsEur. J. Pharmacol.424(2),85-90(2001)
