Solriamfetol
Cat. No.:YN1730030
CAS No. :178429-62-4
产品名称: | Solriamfetol |
CAS No.: | 178429-62-4 |
Chemical Name: | (2R)-2-Amino-3-phenylpropyl Carbamate; JZP 110 |
Synonyms: | JZP-110; ADX-N05; R228060 |
分子量: | 194.23 |
分子式: | C₁₀H₁₄N₂O₂ |
SMILES: | N[C@@H](COC(N)=O)CC1=CC=CC=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Solriamfetol (JZP-110) 是一种口服有效的,选择性的多巴胺和去甲肾上腺素再摄取抑制剂,对多巴胺和去甲肾上腺素转运蛋白的IC50分别为 2.9 μM 和 4.4 μM。Solriamfetol 具有强大的促唤醒作用。 |
IC50和靶点: | |
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Baladi, Michelle G., et al.: J. of Pharmaco. and Exper. Therap.,В 366(2),В 367-376В (2018)
Abad, Vivien C., et al.: Expert Rev. of Resp. Med.,В 12(12),В 1007-1019В (2018)
Takahashi, Tatsunori, et al.: Exp. Opin. on Orphan Drugs,В 6(10),В 597-610В (2018)