Carbamazepine 10,11-epoxide
Cat. No.：YN1730148
CAS No. ：36507-30-9
| 产品名称: | Carbamazepine 10,11-epoxide |
| CAS No.: | 36507-30-9 |
| Chemical Name: | 1a,10b-dihydro-6H-dibenz[b,f]oxireno[d]azepine-6-carboxamide |
| Synonyms: | |
| 分子量: | 252.26806 |
| 分子式: | C15H12N2O2 |
| SMILES: | O=C(N1C2=C(C3OC3C4=C1C=CC=C4)C=CC=C2)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Carbamazepine 10,11-epoxide 是metaboliteofCarbamazepine(HY-B0246) 的代谢物，具有口服活性。Carbamazepine 具有抗惊厥作用。Carbamazepine 可用于癫痫发作的研究。 |
| IC50和靶点: | |
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Kerr, B.M., Thummel, K.E., Wurden, C.J., et al.Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formationBiochem. Pharmacol.47(11),1969-1979(1994)
Bourgeois, B.F., and Wad, N.Individual and combined antiepileptic and neurotoxic activity of carbamazepine and carbamazepine-10,11-epoxide in miceJ. Pharmacol. Exp. Ther.231(2),411-415(1984)
Miao, X.-S., Yang, J.-J., and Metcalfe, C.D.Carbamazepine and its metabolites in wastewater and in biosolids in a municipal wastewater treatment plantEnviron. Sci. Technol.39(19),7469-7475(2005)
