JI051
Cat. No.:YN380054
CAS No. :2234281-75-3
产品名称: | JI051 |
CAS No.: | 2234281-75-3 |
Chemical Name: | |
Synonyms: | JI051;(E)-N-(2-Ethoxyphenethyl)-3-(7-methoxy-1H-indol-3-yl)acrylamide;ZB1586;(E)-N-[2-(2-Ethoxyphenyl)ethyl]-3-(7-methoxy-1H-indol-3-yl)prop-2-enamide |
分子量: | 364.44 |
分子式: | C₂₂H₂₄N₂O₃ |
SMILES: | O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | JI051 是一种Hes1-PHB2相互作用稳定剂,能够与癌症相关蛋白伴侣 prohibitin 2 (PHB2) 相互作用,通过抑制Notch下游效应基因 Hes1 来诱导细胞周期停滞。具有抗肿瘤作用。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |