BMS-906024
Cat. No.：YN380113
| 产品名称: | BMS-906024 |
| CAS No.: | 1401066-79-2 |
| Chemical Name: | |
| Synonyms: | BMS 906024;BMS906024 |
| 分子量: | 556.50 |
| 分子式: | C₂₆H₂₆F₆N₄O₃ |
| SMILES: | O=C(N[C@@H]1C(N(C)C2=CC=CC=C2C(C3=CC=CC=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BMS-906024 是一种口服有效，选择性的 γ 分泌酶 (γ-secretase; gamma secretase) 抑制剂。BMS-906024 是有效的，泛Notch受体抑制剂，对 Notch1，-2，-3 和 -4 受体的IC50值分别为 1.6 nM，0.7 nM，3.4 nM 和 2.9 nM。BMS-906024 表现广谱抗肿瘤活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
