Tangeretin
Cat. No.：YN380218
CAS No. ：481-53-8
| 产品名称: | Tangeretin |
| CAS No.: | 481-53-8 |
| Chemical Name: | 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 桔皮素; Tangeritin; NSC53909; NSC618905 |
| 分子量: | 372.37 |
| 分子式: | C₂₀H₂₀O₇ |
| SMILES: | O=C1C=C(C2=CC=C(OC)C=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tangeretin (Tangeritin)，黄酮类化合物，是Notch-1的有效抑制剂，具有抗炎，保护神经等作用。 |
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Van Slambrouck, S., Parmar, V.S., Sharma, S.K., et al.Tangeretin inhibits extracellular-signal-regulated kinase (ERK) phosphorylationFEBS Lett.579(7),1665-1669(2005)
Chen, K.H., Weng, M.S., and Lin, J.K.Tangeretin suppresses IL-1ß-induced cyclooxygenase (COX)-2 expression through inhibition of p38 MAPK, JNK, and AKT activation in human lung carcinoma cellsBiochem. Pharmacol.73(2),215-227(2007)
Satsu, H., Hiura, Y., Mochizuki, K., et al.Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicalsJ. Agric. Food Chem.56(13),5366-5373(2008)
Conesa, C.M., Ortega, V.V., Gascón, M.J.Y., et al.Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosminJ. Agric. Food Chem.53(17),6791-6797(2005)
Takano, K., Tabata, Y., Kitao, Y., et al.Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxinAm. J. Physiol. Cell Physiol.292(1),C353-C361(2007)
Kurowska, E.M., and Manthey, J.A.Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemiaJ. Agric. Food Chem.52(10),2879-2886(2004)
