6-Mercaptopurine hydrate
Cat. No.：YN290282
CAS No. ：6112-76-1
| 产品名称: | 6-Mercaptopurine hydrate |
| CAS No.: | 6112-76-1 |
| Chemical Name: | 1,2,3,9-tetrahydro-6H-purine-6-thione, monohydrate |
| Synonyms: | 6-巯基嘌呤 一水合物; Mercaptopurine hydrate; 6-MP hydrate |
| 分子量: | 170.19 |
| 分子式: | C₅H₆N₄OS |
| SMILES: | S=C1NC=NC2=C1NC=N2.O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 6-Mercaptopurine hydrate (Mercaptopurine hydrate; 6-MP hydrate) 是一种嘌呤类似物，是内源性嘌呤的拮抗剂且已被广泛用作抗白血病药物和免疫抑制药物。 |
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Brockman, R.W.Biochemical aspects of mercaptopurine inhibition and resistanceCancer Res.23(8),1191-1201(1963)
Skipper, H.E., Thomson, J.R., Elion, G.B., et al.Observations on the anticancer activity of 6-mercaptopurineCancer Res.14(4),294-298(1954)
Spiegelberg, H.L., and Miescher, P.A.The effect of 6-mercaptopurine and aminopterin on experimental immune thyroiditis in guinea pigsJ. Exp. Med.118(5),869-890(1963)
Alsous, M., Abu Farha, R., Alefishat, E., et al.Adherence to 6-mercaptopurine in children and adolescents with acute lymphoblastic leukemiaPLoS One12(9),e0183119(2017)
