OAC1
Cat. No.:YN450055
产品名称: | OAC1 |
CAS No.: | 300586-90-7 |
Chemical Name: | N-1H-pyrrolo[2,3-c]pyridin-5-yl-benzamide |
Synonyms: | BAS 00287861 |
分子量: | 237.26 |
分子式: | C₁₄H₁₁N₃O |
SMILES: | O=C(NC1=CC2=C(NC=C2)C=N1)C3=CC=CC=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | OAC1是转录因子Oct4活化剂,提高iPSC的重编程效率和编程过程中的加速。 |
IC50和靶点: | |
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Niwa, H., Miyazaki, J.i., and Smith, A.G.Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsNat. Genet.24(4),372-376(2000)
Takahashi, K., Tanabe, K., Ohnuki, M., et al.Induction of pluripotent stem cells from adult human fibroblasts by defined factorsCell131,861-872(2007)
Li, W., Tian, E., Chen, Z.X., et al.Identification of Oct4-activating compounds that enhance reprogramming efficiencyProc. Natl. Acad. Sci. USA109(51),20853-20858(2012)