O4I2
Cat. No.：YN450126
CAS No. ：165682-93-9
规格
价格(RMB)
库存
| 产品名称: | O4I2 |
| CAS No.: | 165682-93-9 |
| Chemical Name: | 2-[(4-chlorophenyl)amino]- 4-thiazolecarboxylic acid, ethyl ester |
| Synonyms: | O4I-2,O4I 2 |
| 分子量: | 282.75 |
| 分子式: | C₁₂H₁₁ClN₂O₂S |
| SMILES: | O=C(C1=CSC(NC2=CC=C(Cl)C=C2)=N1)OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | O4I2 是有效的Oct3/4诱导剂。O4I2 可诱导多能干细胞相关基因Lin28、Sox2和Nanog的表达，并抑制Rex1。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Niwa, H., Miyazaki, J.i., and Smith, A.G.Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsNat. Genet.24(4),372-376(2000)
Takahashi, K., Tanabe, K., Ohnuki, M., et al.Induction of pluripotent stem cells from adult human fibroblasts by defined factorsCell131,861-872(2007)
Cheng, X., Yoshida, H., Raoofi, D., et al.Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4J. Med. Chem.58(15),5742-5750(2015)
