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Etofylline

Cat. No.:YN481998

  • CAS No. :519-37-9

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Etofylline
      CAS No.: 519-37-9
      Chemical Name: 3,7-dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1H-purine-2,6-dione
      Synonyms:乙羟茶碱; 7-(β-Hydroxyethyl)theophylline
      分子量:224.22
      分子式:C₉H₁₂N₄O₃
      SMILES:O=C(N1C)N(C)C2=C(N(CCO)C=N2)C1=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Etofylline (7-(β-Hydroxyethyl)theophylline) 是 Theophylline 的 N-7 取代衍生物。Etofylline 是一种支气管扩张药,可用于哮喘研究。Etofylline 也是一种抗胆固醇药,可降低血液中的总胆固醇水平。
      IC50和靶点:
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    • Mizon, J., Skandrani, E., and Mizon, C.Determination of the inhibitory activity of some new substituted theophyllines on the specific phosphodiesterase of cyclic nucleotidesTherapie26(5),911-917(1971)

      Ufkes, J.G., Leeuwin, R.S., Ottenhof, M., et al.Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pigArch. Int. Pharmacodyn. Ther.253(2),301-314(1981)

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