Dipivefrin hydrochloride
Cat. No.：YN482022
CAS No. ：64019-93-8
| 产品名称: | Dipivefrin hydrochloride |
| CAS No.: | 64019-93-8 |
| Chemical Name: | 2,2-dimethyl-propanoic acid, 1,1'-[4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene] ester, monohydrochloride |
| Synonyms: | Dipivefrine hydrochloride |
| 分子量: | 387.90 |
| 分子式: | C₁₉H₃₀ClNO₅ |
| SMILES: | CNCC(C1=CC=C(OC(C(C)(C)C)=O)C(OC(C(C)(C)C)=O)=C1)O.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dipivefrin hydrochloride (Dipivefrine hydrochloride) 是一种抗青光眼前体药物，通过角膜中的酯酶水解为其活性化合物肾上腺素。 |
| IC50和靶点: | |
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Nakamura, M., Shirasawa, E., and Hikida, M.Characterization of esterases involved in the hydrolysis of dipivefrin hydrochlorideOphthalmic Res.25(1),46-51(1993)
Kawa, J.E., Higginbotham, E.J., Change, I.L., et al.Effects of antiglaucoma medications on bovine trabecular meshwork cells in vitroExp. Eye Res.57(5),557-565(1993)
Wu, K.Y., Hong, S.J., and Wang, H.Z.Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cellsKaohsiung J. Med. Sci.22(2),60-67(2006)
Wu, K.Y., Wang, H.Z., and Hong, S.J.Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cellsKaohsiung J. Med. Sci.23(3),105-111(2007)
Wu, K.Y., Wang, H.Z., and Hong, S.J.Effects of antiglaucoma drugs on cellular proliferation in cultured human corneal keratocytesKaohsiung J. Med. Sci.22(3),120-125(2006)
