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Fursultiamine

Cat. No.:YN482121

  • CAS No. :804-30-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Fursultiamine
      CAS No.: 804-30-8
      Chemical Name: N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-formamide
      Synonyms:呋喃硫胺
      分子量:398.54
      分子式:C₁₇H₂₆N₄O₃S₂
      SMILES:O=CN(CC1=CN=C(C)N=C1N)/C(C)=C(SSCC2OCCC2)\CCO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Fursultiamine 是一种维生素 B1衍生物,具有抗伤害和抗肿瘤活性。Fursultiamine 可用于维生素 B1缺乏病,骨关节炎 (OA) 和癌症研究。
      IC50和靶点:
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    • Kobayashi, T., Notoya, K., Nakamura, A., et al.Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritisInflamm. Res.54(6),249-255(2005)

      Do, J.Y., Kim, J., Kim, M.-J., et al.Fursultiamine alleviates choroidal neovascularization by suppressing inflammation and metabolic reprogrammingInvest. Ophthalmol. Vis. Sci.61(12),24(2020)

      Nozaki, S., Mizuma, H., Tanaka, M., et al.Thiamine tetrahydrofurfuryl disulfide improves energy metabolism and physical performance during physical-fatigue loading in ratsNutr. Res.29(12),867-872(2009)

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