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Calcein-AM

Cat. No.:YN482167

  • CAS No. :148504-34-1

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Calcein-AM
      CAS No.: 148504-34-1
      Chemical Name: N,N’-[[3’,6’-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9’-[9H]xanthene]-2’,7’-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]]-glycine, 1,1’-bis[(acetyloxy)methyl] ester
      Synonyms:钙黄绿素-AM; Calcein acetoxymethyl ester
      分子量:994.86
      分子式:C₄₆H₄₆N₂O₂₃
      SMILES:O=C1OC2(C(C=C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OC(C)=O)=C3)=C3OC4=CC(OC(C)=O)=C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=C24)C5=C1C=CC=C5
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Calcein-AM是用于测定细胞活力的可以渗透细胞的荧光染料。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Hynes, J., Floyd, S., Soini, A.E., et al.Fluorescence-based cell viability screening assays using water-soluble oxygen probesJ. Biomol. Screen.8,264-272(2003)

      Sabnis, R.W.Handbook of biological dyes and stains: Synthesis and industrial applications,(2010)

      Polli, J.W., Wring, S.A., Humphreys, J.E., et al.Rational use of in vitro P-glycoprotein assays in drug discoveryJ. Pharmacol. Exp. Ther.299(2),620-628(2001)

      Tiberghien, F., and Loor, F.Ranking of P-glycoprotein substates and inhibitors by a calcein-AM fluorometry screening assayAnticancer Drugs7(5),568-578(1996)

      Szakács, G., Jakab, K., Antal, F., et al.Diagnostics of multidrug resistance in cancerPathol.Oncol.Res.4(4),251-257(2016)

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