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Dihydroethidium

Cat. No.:YN482176

  • CAS No. :104821-25-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Dihydroethidium
      CAS No.: 104821-25-2
      Chemical Name: 5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine
      Synonyms:二氢乙锭; Hydroethidine; PD-MY 003
      分子量:315.41
      分子式:C₂₁H₂₁N₃
      SMILES:NC1=CC=C2C3=C(C=C(N)C=C3)C(C4=CC=CC=C4)N(CC)C2=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Dihydroethidium(Hydroethidine; PD-MY 003)是过氧化物指示剂,在细胞质中具有蓝色荧光,直到被氧化。
      IC50和靶点:
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      In Vivo:
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    • Cai, H., Dikalov, S., Griendling, K.K., et al.Detection of reactive oxygen species and nitric oxide in vascular cells and tissues: Comparison of sensitivity and specificityMethods Mol. Med.139,293-311(2007)

      Laurindo, F.R.M., Fernandes, D.C., and Santos, C.X.C.Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation productsMethods Enzymol.441,237-260(2008)

      Fink, B., Laude, K., McCann, L., et al.Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assayAm. J. Physiol. Cell Physiol.287,C895-C902(2004)

      Robinson, K.M., Janes, M.S., Pehar, M., et al.Selective fluorescent imaging of superoxide in vivo using ethidium-based probesProc. Natl. Acad. Sci. USA103(41),15038-15043(2006)

      Salih, H.R., Husfeld, L., and Adam, D.Simultaneous cytofluorometric measurement of phagocytosis, burst production and killing of human phagocytes using Candida albicans and Staphylococcus aureus as target organismsClin. Microbiol. Infect.6(5),251-258(2000)

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