Thioflavin T
Cat. No.:YN482194
产品名称: | Thioflavin T |
CAS No.: | 2390-54-7 |
Chemical Name: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-benzothiazolium, monochloride |
Synonyms: | 硫黄素T; Basic Yellow 1 |
分子量: | 318.86 |
分子式: | C₁₇H₁₉ClN₂S |
SMILES: | CC1=CC=C2[N+](C)=C(C3=CC=C(N(C)C)C=C3)SC2=C1.[Cl-] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Thioflavin T 是一种阳离子 Benzothiazole 染料,在组织切片中与淀粉样蛋白结合后荧光强度增强。 |
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Biancalana, M., and Koide, S.Molecular mechanism of Thioflavin-T binding to amyloid fibrilsBiochim. Biophys. Acta1804(7),1405-1412(2010)
Naiki, H., Higuchi, K., Hosokawa, M., et al.Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin TAnal. Biochem.177(2),244-249(1989)
Sulatskaya, A.I., Kuznetsova, I.M., Belousov, M.V., et al.Stoichiometry and affinity of thioflavin T binding to Sup35p amyloid fibrilsPLoS One11(5),e0156314(2016)
Alimohammadi-Kamalabadi, M., Eshraghian, M., Zarindast, M.-R., et al.Effect of creatine supplementation on cognitive performance and apoptosis in a rat model of amyloid-beta-induced Alzheimer's diseaseIran J. Basic Med. Sci.19(11),1159-1165(2016)