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Thioflavin T

Cat. No.:YN482194

  • CAS No. :2390-54-7

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    • 生物活性
    • 参考文献
    • 产品名称: Thioflavin T
      CAS No.: 2390-54-7
      Chemical Name: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-benzothiazolium, monochloride
      Synonyms:硫黄素T; Basic Yellow 1
      分子量:318.86
      分子式:C₁₇H₁₉ClN₂S
      SMILES:CC1=CC=C2[N+](C)=C(C3=CC=C(N(C)C)C=C3)SC2=C1.[Cl-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Thioflavin T 是一种阳离子 Benzothiazole 染料,在组织切片中与淀粉样蛋白结合后荧光强度增强。
      IC50和靶点:
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    • Biancalana, M., and Koide, S.Molecular mechanism of Thioflavin-T binding to amyloid fibrilsBiochim. Biophys. Acta1804(7),1405-1412(2010)

      Naiki, H., Higuchi, K., Hosokawa, M., et al.Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin TAnal. Biochem.177(2),244-249(1989)

      Sulatskaya, A.I., Kuznetsova, I.M., Belousov, M.V., et al.Stoichiometry and affinity of thioflavin T binding to Sup35p amyloid fibrilsPLoS One11(5),e0156314(2016)

      Alimohammadi-Kamalabadi, M., Eshraghian, M., Zarindast, M.-R., et al.Effect of creatine supplementation on cognitive performance and apoptosis in a rat model of amyloid-beta-induced Alzheimer's diseaseIran J. Basic Med. Sci.19(11),1159-1165(2016)

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