Gallein
Cat. No.：YN482201
| 产品名称: | Gallein |
| CAS No.: | 2103-64-2 |
| Chemical Name: | 3′,4′,5′,6′-tetrahydroxy-spiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3-one |
| Synonyms: | 茜素紫; Pyrogallol phthalein |
| 分子量: | 364.31 |
| 分子式: | C₂₀H₁₂O₇ |
| SMILES: | O=C1OC2(C3=C(OC4=C2C=CC(O)=C4O)C(O)=C(O)C=C3)C5=C1C=CC=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gallein 是一种 G 蛋白 βγ (Gβγ) 亚基信号抑制剂。Gallein 干扰 Gβγ 亚基与 PI3Kγ 的相互作用。具有抗肿瘤活性。Gallein 用作红色染料，酸碱指示剂和磷酸盐的检测试剂。 |
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Lehmann, D.M., Seneviratne, A.M.P.B., and Smrcka, A.V.Small molecule disruption of G protein βγ subunit signaling inhibits neutrophil chemotaxis and inflammationMol. Pharmacol.73(2),410-418(2008)
Kamal, F.A., Mickelsen, D.M., Wegman, K.M., et al.Simultaneous adrenal and cardiac G-protein–coupled receptor-Gβγ inhibition halts heart failure progressionJ. Am. Coll. Cardiol.63(23),2549-2557(2014)
