EGTA-AM
Cat. No.:YN482287
产品名称: | EGTA-AM |
CAS No.: | 99590-86-0 |
Chemical Name: | 3,12-bis[2-[(acetyloxy)methoxy]-2-oxoethyl]-6,9-dioxa-3,12-diazatetradecanedioic acid, 1,14-bis[(acetyloxy)methyl] ester |
Synonyms: | EGTA Acetoxymethyl ester |
分子量: | 668.60 |
分子式: | C₂₆H₄₀N₂O₁₈ |
SMILES: | O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)CCOCCOCCN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | EGTA-AM 是 EGTA 的膜渗透形式,可以被动地载入到细胞中产生细胞内的 EGTA;EGTA-AM 同时为 Ca2+螯合剂。 |
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Drumm, B.T., Large, R.J., Hollywood, M.A., et al.The role of Ca2+ influx in spontaneous Ca2+ wave propagation in interstitial cells of Cajal from the rabbit urethraJ. Physiol.593(15),3333-3350(2015)
Jalini, S., Ye, H., Tonkikh, A.A., et al.Raised intracellular calcium contributes to ischemia-induced depression of evoked synaptic transmissionPLoS One11(3),(2016)
Nanou, E., Sullivan, J.M., Scheuer, T., et al.Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to short-term synaptic plasticity in hippocampal neuronsProc. Natl. Acad. Sci. USA113(4),1062-1067(2016)