Isoacteoside
Cat. No.：YN482353
CAS No. ：61303-13-7
| 产品名称: | Isoacteoside |
| CAS No.: | 61303-13-7 |
| Chemical Name: | 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside, 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] |
| Synonyms: | 异麦角甾苷; Isoverbascoside |
| 分子量: | 624.59 |
| 分子式: | C₂₉H₃₆O₁₅ |
| SMILES: | OC1=CC(/C=C/C(OC[C@@H]2[C@@H](O)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](OCCC4=CC=C(O)C(O)=C4)O2)=O)=CC=C1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isoacteoside是天然产物，能显著地抑制糖基化终产物的形成。 |
| IC50和靶点: | |
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Chae, S., Kim, J.S., Kang, K.A., et al.Antioxidant activity of isoacteoside from Clerodendron trichotomumJ. Toxicol. Environ. Health A68(5),389-400(2005)
Yang, X., Guo, F., Peng, Q., et al.Suppression of in vitro and in vivo human ovarian cancer growth by isoacteoside is mediated via sub-G1 cell cycle arrest, ROS generation, and modulation of AKT/PI3K/m-TOR signalling pathwayJ. BUON.24(1),285-290(2019)
Shiao, Y.-J., Su, M.-H., Lin, H.-C., et al.Acteoside and isoacteoside protect amyloid β peptide induced cytotoxicity, cognitive deficit and neurochemical disturbances in vitro and in vivoInt. J. Mol. Sci.18(4),E895(2017)
Gao, H., Cui, Y., Kang, N., et al.Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerizationBr. J. Pharmacol.174(17),2880-2896(2017)
