Evodiamine
Cat. No.：YN482368
| 产品名称: | Evodiamine |
| CAS No.: | 518-17-2 |
| Chemical Name: | 8,13,13bS,14-tetrahydro-14-methyl-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one |
| Synonyms: | 吴茱萸碱; (+) |
| 分子量: | 303.36 |
| 分子式: | C₁₉H₁₇N₃O |
| SMILES: | O=C1C2=CC=CC=C2N(C)[C@](N1CC3)([H])C4=C3C5=CC=CC=C5N4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Evodiamine是从萱草的果实中分离的生物碱, 具有多种生物活性，比如抗炎，抗肥胖和抗肿瘤。 |
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Yu, H., Gong, W., Wang, Z., et al.Pharmacological actions of multi-target-directed evodiamineMolecules18(2),1826-1843(2013)
Wang, T., Wang, X., and Yamashita, H.Evodiamine inhibits adipogenesis via the EGFR-PKCα-ERK signaling pathwayFEBS Lett.583(22),3655-3659(2009)
Ogasawara, M., Matsubara, T., and Suzuki, H.Screening of natural compounds for inhibitory activity on colon cancer cell migrationBiol. Pharm. Bull.24(6),720-723(2001)
Pearce, L.V., Petukhov, P.A., Szabo, T., et al.Evodiamine functions as an agonist for the vanilloid receptor TRPV1Org. Biomol. Chem.2,2281-2286(2004)
Takada, Y., Kobayashi, Y., and Aggarwal, B.B.Evodiamine abolishes constitutive and inducible NF-κB activation by inhibiting IκBα kinase activation, thereby suppressing NF-κB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasionJ. Biol. Chem.280(17),17203-17212(2005)
