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Benzoylaconine

Cat. No.:YN482388

  • CAS No. :466-24-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Benzoylaconine
      CAS No.: 466-24-0
      Chemical Name: (1α,3α,6α,14α,15α,16β)-20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-aconitane-3,8,13,14,15-pentol, 14-benzoate
      Synonyms:苯甲酰乌头原碱; Isaconitine; Pikraconitin
      分子量:603.70
      分子式:C₃₂H₄₅NO₁₀
      SMILES:CO[C@@H]1C(C(N(CC)C2)C3[C@@H]4OC)([C@@](C[C@@]5(O)[C@@H]6OC(C7=CC=CC=C7)=O)([H])[C@@]6([H])[C@@]3([C@@H](O)[C@@H]5OC)O)[C@@]4([H])[C@@]2(COC)[C@H](O)C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Benzoylaconine(Isaconitine; Pikraconitin)是中药附子生物碱。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Tursunkhodzhaeva, F.M., Dzhakhangirov, F.N., and Salimov, B.T.Diterpenoid alkaloids as antidotes to aconitine-type neurotoxin poisoning. Structure–activity relationshipChem. Nat. Compd.52(5),849-852(2016)

      Wu, J.-J., Zhu, Y.-F., Guo, Z.-Z., et al.Aconitum alkaloids, the major components of Aconitum species, affect expression of multidrug resistance-associated protein 2 and breast cancer resistance protein by activating the Nrf2-mediated signalling pathwayPhytomedicine44,87-97(2018)

      Wu, J., Lin, N., Li, F., et al.Induction of P-glycoprotein expression and activity by Aconitum alkaloids: Implication for clinical drug-drug interactionsSci. Rep.6:25343,(2016)

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