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(2S,3R,4S)-4-Hydroxyisoleucine

Cat. No.:YN484337

  • CAS No. :55399-93-4

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    • 生物活性
    • 参考文献
    • 产品名称: (2S,3R,4S)-4-Hydroxyisoleucine
      CAS No.: 55399-93-4
      Chemical Name: 2-amino-2,3,5-trideoxy-3-methyl-L-ribonic acid
      Synonyms:(2S,3R,4S)-4-Hydroxy-L-isoleucine
      分子量:147.17
      分子式:C₆H₁₃NO₃
      SMILES:O[C@@H](C)[C@H](C)[C@H](N)C(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (2S,3R,4S)-4-Hydroxyisoleucine 是从胡芦巴中分离得到的一种可口服的有效成分,具有抗糖尿病、抗糖尿病肾病的活性。
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    • Broca, C., Manteghetti, M., Gross, R., et al.4-Hydroxyisoleucine: Effects of synthetic and natural analogues on insulin secretionEur. J. Pharmacol.390(3),339-345(2000)

      Broca, C., Breil, V., Cruciani-Guglielmacci, C., et al.Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in ratAm. J. Physiol. Endocrinol. Metab.287(3),E463-E471(2004)

      Haeri, M.R., Limaki, H.K., White, C.J., et al.Non-insulin dependent anti-diabetic activity of (2S, 3R, 4S) 4-hydroxyisoleucine of fenugreek (Trigonella foenum graecum) in streptozotocin-induced type I diabetic ratsPhytomedicine19(7),571-574(2012)

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