TCEP hydrochloride
Cat. No.:YN484351
产品名称: | TCEP hydrochloride |
CAS No.: | 51805-45-9 |
Chemical Name: | 3,3',3''-phosphinylidynetris-propanoic acid, monohydrochloride |
Synonyms: | Tris(2-carboxyethyl)phosphine hydrochloride |
分子量: | 286.65 |
分子式: | C₉H₁₆ClO₆P |
SMILES: | O=C(O)CCP(CCC(O)=O)CCC(O)=O.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) 是一种非硫醇还原剂,比其他化学还原剂更稳定并且产生更快的 S-S 还原反应。TCEP hydrochloride 是一种三烷基膦,可选择性地减少蛋白质的分解,而不会改变其性质或与反应混合物中的硫醇导向剂发生相互作用。TCEP hydrochloride 还是 DNA/AuNP 化学中常用的还原剂。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Zhang, H.M., McLoughlin, S.M., Frausto, S.D., et al.Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometryAnal. Chem.82(4),1450-1454(2010)
Lykkesfeldt, J.Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: Reliable reduction with tris[2-carboxyethyl]phosphine hydrochlorideAnal. Biochem.282(1),89-93(2000)
Sato, Y., Uchiki, T., Iwama, M., et al.Determination of dehydroascorbic acid in mouse tissues and plasma by using tris(2-carboxyethyl)phosphine hydrochloride as reductant in metaphosphoric acid/ethylenediaminetetraacetic acid solutionBiol. Pharm. Bull.33(3),364-369(2010)