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2-Acetamidophenol

Cat. No.:YN484394

  • CAS No. :614-80-2

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    • 参考文献
    • 产品名称: 2-Acetamidophenol
      CAS No.: 614-80-2
      Chemical Name: N-(2-hydroxyphenyl)-acetamide
      Synonyms:Orthocetamol
      分子量:151.16
      分子式:C₈H₉NO₂
      SMILES:OC1=C(NC(C)=O)C=CC=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 2-Acetamidophenol (Orthocetamol) 是 Paracetamol (4-acetamidophenol) 的邻位区域异构体。2-Acetamidophenol 是一种有前途的止痛药和抗关节炎药。
      IC50和靶点:
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      In Vivo:
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    • Qureshı, Z., Aslam, M., Saeed, T., et al.Anti-platelet and anti-arthritic Activity of orthocetamol (2-acetamıdophenol): An ortho (O) positional isomer of paracetamolTurk. J. Pharm. Sci.12(3),75-94(2015)

      Slininger, P.J., Burkhead, K.D., Schisler, D.A., et al.Isolation, identification, and accumulation of 2-acetamidophenol in liquid cultures of the wheat take-all biocontrol agent Pseudomonas fluorescens 2-79Appl. Microbiol. Biotechnol.54(3),376-381(2000)

      Dziwornu, G.A., Coertzen, D., Leshabane, M., et al.Incorporating phenolic mannich base side chains inhibit microtubule and hemozoin formation: Structure-activity relationship and in vivo oral efficacy studiesJ. Med. Chem.64(8),5198-5215(2021)

      Arıkan, C.C., Kulabaş, N., and Küçükgüzel, I.Synthesis and standardization of an impurity of acetaminophen, development and validation of liquid chromatographic methodJ. Pharm. Biomed. Anal.223,115123(2023)

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