KRP-297
Cat. No.：YN470054
| 产品名称: | KRP-297 |
| CAS No.: | 213252-19-8 |
| Chemical Name: | 5-[(2,4-dioxo-5-thiazolidinyl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-benzamide |
| Synonyms: | MK-0767 |
| 分子量: | 438.4212696 |
| 分子式: | C20H17F3N2O4S |
| SMILES: | COC(C(C(NCC1=CC=C(C(F)(F)F)C=C1)=O)=C2)=CC=C2CC3C(NC(S3)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KRP-297是aPPARα和PPARγ激动剂，有潜力用于 2 型糖尿病和血脂异常的研究。KRP-297可以恢复降低的脂质氧化作用，也可以抑制肝脏内脂肪生成和甘油三酯积累。 |
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Doebber, T.W., Kelly, L.J., Zhou, G., et al.MK-0767, a novel dual PPARα/γ agonist, displays robust antihyperglycemic and hypolipidemic activitiesBiochem. Biophys. Res. Commun.318(2),323-328(2004)
