ULS 欢迎您!
ULS 欢迎您!
> 产品中心 > 抑制剂 & 激动剂 > Others > Others

7,8-Didehydrocimigenol

Cat. No.:YN470059

  • CAS No. :247923-29-1

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 7,8-Didehydrocimigenol
      CAS No.: 247923-29-1
      Chemical Name: 2-[[4-[2-[[[(2,4-difluorophenyl)amino]carbonyl]heptylamino]ethyl]phenyl]thio]-2-methyl-propanoic acid
      Synonyms:GW9578; GW 9578; GW-9578.
      分子量:492.6
      分子式:C26H34F2N2O3S
      SMILES:CCCCCCCN(CCc1ccc(cc1)SC(C)(C)C(=O)O)C(=O)Nc1ccc(F)cc1F
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: GW9578 是一种亚型选择性的PPARα激动剂 (对鼠和人 PPAR-α 的EC50分别为 5 和 50 nM),具有有效的降脂活性。
      IC50和靶点: [{name:"mouse PPARα:5 nM (EC50)"},{name: "h-PPARα:50 nM (EC50)"}]
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Latruffe, N., and Vamecq, J.Peroxisome proliferators and peroxisome proliferator activated receptors (PPARs) as regulators of lipid metabolismBiochimie79(2-3),81-94(1997)

      Lemberger, T., Desvergne, B., and Wahli, W.Peroxisome proliferator-activated receptors: A nuclear receptor signaling pathway in lipid physiologyAnnu. Rev. Cell Dev. Biol.12,335-363(1996)

      Mandard, S., Müller, M., and Kersten, S.Peroxisome proliferator-activated receptor α target genesCell. Mol. Life Sci.61(4),393-416(2004)

      Brown, P.J., Winegar, D.A., Plunket, K.D., et al.A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARα agonist with potent lipid-lowering activityJ. Med. Chem.42(19),3785-3788(1999)

      Guerre-Millo, M., Gervois, P., Raspé, E., et al.Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposityJ. Biol. Chem.275(22),16638-16642(2000)

    • 摩尔计算器
    • 稀释计算器
    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    计算

    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
    • C1
      V1
      C2
      V2
    • 您最近查看的产品:
    相关产品


    ULS 的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)Copyright © 2020-2021 ULS. All Rights Reserved. 备案号:粤ICP备2021013238号-1
    0.592253s