Melengestrol acetate
Cat. No.：YN470060
| 产品名称: | Melengestrol acetate |
| CAS No.: | 2919-66-6 |
| Chemical Name: | 17-(acetyloxy)-6-methyl-16-methylene-pregna-4,6-diene-3,20-dione |
| Synonyms: | |
| 分子量: | 396.51918 |
| 分子式: | C25H32O4 |
| SMILES: | CC(O[C@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(C(C)=C3)=CC(CC4)=O)C)([H])CC2)([H])CC1=C)C)C(C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Melengestrol acetate 是一种孕酮衍生物，作为一种具有口服活性的皮质类固醇激素，可促进子宫内膜增殖、妊娠维持和月经活动延迟。Melengestrol acetate 是一种避孕试剂 (contraceptive agent)，用于动物的生长促进作用和抑制发情。在动物模型中，Melengestrol acetate 抑制雄激素依赖性和非依赖性前列腺肿瘤生长，可用于癌症研究。 |
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Illingworth, D.V., Elsner, C., De La Cruz, K.D.G., et al.A specific progesterone receptor of myometrial cytosol from the rhesus monkeyJ. Steroid Biochem.8(2),157-160(1977)
Chakraborty, P.K., Kliewer, R.H., and Hisaw Jr., F.L.Effect of melengestrol acetate on growth and reproduction in ratsJ. Dairy Sci.61(12),1778-1781(1978)
Padilla, G.M., Yacullo, R.C., Padilla, J.J., et al.Melengestrol acetate and megestrol acetate are prostatic tumor inhibiting agentsBiochem. Cell Biol.68(10),1181-1188(1990)
