Pipendoxifene hydrochloride
Cat. No.：YN470067
CAS No. ：54048-10-1
| 产品名称: | Pipendoxifene hydrochloride |
| CAS No.: | 54048-10-1 |
| Chemical Name: | (17α)-13-ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one |
| Synonyms: | 3-Oxodesogestrel; 3-keto-Desogestrel |
| 分子量: | 324.5 |
| 分子式: | C22H28O2 |
| SMILES: | O[C@@]1(C#C)CC[C@@]([C@]1(CC)C2)([H])[C@]3([H])CCC4=CC(CC[C@]4([H])[C@@]3([H])C2=C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Etonogestrel (3-Oxodesogestrel) 是孕激素去氧孕烯的生物活性代谢物，Etonogestrel 与靶器官中的孕酮受体 (progesterone receptor) 和雌激素受体 (estrogen receptors) 高亲和力地结合。Etonogestrel 诱导FKBP51mRNA 和蛋白表达。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Stanczyk, F.Z.All progestins are not created equalSteroids68(10-13),879-890(2003)
Phillips, A., Demarest, K., Hahn, D.W., et al.Progestational and androgenic receptor binding affinities and in vivo activities of norgestimate and other progestinsContraception41(4),399-410(1990)
Krikun, G., Booth, C.J., Buchwalder, L., et al.Effects of etonogestrel treatment in the reproductive organs and uterine arteries of nonoophorectomized guinea pigsReprod. Sci.19(4),400-406(2012)
