WAY-169916
Cat. No.：YN470069
CAS No. ：669764-18-5
| 产品名称: | WAY-169916 |
| CAS No.: | 669764-18-5 |
| Chemical Name: | 4-[1-(2-propen-1-yl)-7-(trifluoromethyl)-1H-indazol-3-yl]-1,3-benzenediol |
| Synonyms: | |
| 分子量: | 334.2926096 |
| 分子式: | C17H13F3N2O2 |
| SMILES: | FC(F)(C1=CC=CC2=C1N(CC=C)N=C2C3=C(O)C=C(O)C=C3)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | WAY-169916 是一种雌激素受体的途径选择性配体，通过抑制 NF-kB 转录活性发挥作用。WAY-169916 具有抗炎活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Chadwick, C.C., Chippari, S., Matelan, E., et al.Identification of pathway-selective estrogen receptor ligands that inhibit NF-κB transcriptional activityProc. Natl. Acad. Sci. U.S.A.102(7),2543-2548(2005)
Booth, E.A., Marchesi, M., Knittel, A.K., et al.The pathway-selective estrogen receptor ligand WAY-169916 reduces infarct size after myocardial ischemia and reperfusion by an estrogen receptor dependent mechanismJ. Cardiovasc. Pharmacol.49(6),401-407(2007)
