MK-3984
Cat. No.：YN470073
| 产品名称: | MK-3984 |
| CAS No.: | 915087-27-3 |
| Chemical Name: | 4-[7-[4-cyano-3-(trifluoromethyl)phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-benzamide |
| Synonyms: | RD 162;RD-162 |
| 分子量: | 476.4 |
| 分子式: | C22H16F4N4O2S |
| SMILES: | S=C1N(C2=CC=C(C#N)C(C(F)(F)F)=C2)C(C3(CCC3)N1C4=CC(F)=C(C(NC)=O)C=C4)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RD162 是一种二芳基硫代乙内酰脲，一种口服有效的非甾体抗雄激素 (NSAA)。RD162 与雄激素受体 (AR) 特异性结合。RD162 在去势抵抗人前列腺癌小鼠模型中诱导肿瘤消退。 |
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| Solvent & Solubility: |
Tran, C., Ouk, S., Clegg, N.J., et al.Development of a second-generation antiandrogen for treatment of advanced prostate cancerScience324(5928),787-790(2009)
