CSRM617 hydrochloride
Cat. No.：YN470082
| 产品名称: | CSRM617 hydrochloride |
| CAS No.: | 1353749-74-2 |
| Chemical Name: | |
| Synonyms: | CSRM617 hydrochloride|CSRM-617 |
| 分子量: | 291.688 |
| 分子式: | C10H14ClN3O5 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CSRM617 hydrochloride 是转录因子ONECUT2(OC2，雄激素受体 AR 的主要调节剂) 的选择性小分子抑制剂，在 SPR 测定中Kd为 7.43 uM，直接与 OC2-HOX 结构域结合。CSRM617 hydrochloride 通过切割 Caspase-3 和PARP诱导细胞凋亡 (apoptosis)。CSRM617 hydrochloride 在小鼠的前列腺癌模型中耐受性良好。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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