(R)-Sulforaphane
Cat. No.：YN481366
| 产品名称: | (R)-Sulforaphane |
| CAS No.: | 142825-10-3 |
| Chemical Name: | 1-isothiocyanato-4-[(R)-methylsulfinyl]-butane |
| Synonyms: | L-Sulforaphane |
| 分子量: | 177.29 |
| 分子式: | C₆H₁₁NOS₂ |
| SMILES: | O=[S@@](CCCCN=C=S)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (R)-Sulforaphane 是一种高效的Keap1/Nrf2/ARE途径诱导剂。(R)-Sulforaphane 比 S-异构体更能诱导大鼠肝脏和肺部的致癌解毒酶系统。 |
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Liang, H., and Yuan, Q.Natural sulforaphane as a functional chemopreventive agent: Including a review of isolation, purification and analysis methodsCrit. Rev. Biotechnol.32(3),218-234(2012)
La Marca, M., Beffy, P., Della Croce, C., et al.Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytesFood Chem. Toxicol.50(8),2822-2830(2012)
Dinkova-Kostova, A.T., Holtzclaw, W.D., Cole, R.N., et al.Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidantsProc. Natl. Acad. Sci. USA99(18),11908-11913(2012)
Munday, R., and Munday, C.M.Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: Comparison of allyl isothiocyanate with sulforaphane and related compoundsJ. Agric. Food. Chem.52(7),1867-1871(2004)
