1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Cat. No.：YN480498
| 产品名称: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine |
| CAS No.: | 4004-05-1 |
| Chemical Name: | 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine |
| Synonyms: | DOPE |
| 分子量: | 744.03 |
| 分子式: | C₄₁H₇₈NO₈P |
| SMILES: | O=P(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)(OCCN)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) 是阳离子脂质体的中性辅助脂质 (helper lipid)，与阳离子磷脂结合，提高裸 siRNA 的转染效率。 |
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MacDonald, R.C., Rakhmanova, V.A., Choi, K.L., et al.O-ethylphosphatidylcholine: A metabolizable cationic phospholipid which is a serum-compatible DNA transfection agentJ. Pharm. Sci.88(9),896-904(1999)
Misra, S.K., Biswas, J., Kondaiah, P., et al.Gene transfection in high serum levels: Case studies with new cholesterol based cationic gemini lipidsPLoS One8(7),e68305(2013)
Chen, Y., Sun, J., Lu, Y., et al.Complexes containing cationic and anionic pH-sensitive liposomes: Comparative study of factors influencing plasmid DNA gene delivery to tumorsInt. J. Nanomedicine8,1573-1593(2013)
