12(S)-HETE D8
Cat. No.：YN480770
CAS No. ：84807-90-9
| 产品名称: | 12(S)-HETE D8 |
| CAS No.: | 84807-90-9 |
| Chemical Name: | 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Synonyms: | |
| 分子量: | 328.52 |
| 分子式: | C₂₀H₂₄D₈O₃ |
| SMILES: | CCCCC/C([2H])=C([2H])\C[C@]([2H])(O)/C([2H])=C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 12(S)-HETE D8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE D8 is the predominant lipoxyge |
| IC50和靶点: | |
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Powell, W.S., and Rokach, J.Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acidBiochim. Biophys. Acta1851(4),340-355(2014)
Derogis, P.B.M.C., Chaves-Filho, A.B., and Miyamoto, S.Characterization of hydroxy and hydroperoxy polyunsaturated fatty acids by mass spectrometryBioactive lipids in health and disease,21-38(2019)
Kühn, H., Banthiya, S., and van Leyen, K.Mammalian lipoxygenases and their biological relevanceBiochim. Biophys. Acta1851(4),308-330(2015)
Bürger, F., Krieg, P., Marks, F., et al.Positional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymesBiochem J.348(Pt 2),329-335(2000)
