1'-Hydroxy bufuralol
Cat. No.：YN480753
| 产品名称: | 1'-Hydroxy bufuralol |
| CAS No.: | 57704-16-2 |
| Chemical Name: | α2-[[(1,1-dimethylethyl)amino]methyl]-α7-methyl-2,7-benzofurandimethanol |
| Synonyms: | |
| 分子量: | 277.36 |
| 分子式: | C₁₆H₂₃NO₃ |
| SMILES: | CC(C1=C2OC(C(CNC(C)(C)C)O)=CC2=CC=C1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 1'-Hydroxy bufuralol 是bufuralol 的主要代谢物，可反应 CYP2D 的活性。 |
| IC50和靶点: | |
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Daskalopoulos, E.P., Lang, M.A., Marselos, M., et al.D₂-dopaminergic receptor-linked pathways: Critical regulators of CYP3A, CYP2C, and CYP2DMol. Pharmacol.82(4),668-678(2012)
Yamazaki, H., Guo, Z., Persmark, M., et al.Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomesMol. Pharmacol.46(3),568-577(1994)
