1-Oxo Ibuprofen
Cat. No.：YN480746
| 产品名称: | 1-Oxo Ibuprofen |
| CAS No.: | 65813-55-0 |
| Chemical Name: | α-methyl-4-(2-methyl-1-oxopropyl)-benzeneacetic acid |
| Synonyms: | Ibuprofen EP impurity J |
| 分子量: | 220.26 |
| 分子式: | C₁₃H₁₆O₃ |
| SMILES: | O=C(O)C(C)C1=CC=C(C(C(C)C)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 1-Oxo Ibuprofen (Ibuprofen EP impurity J) 是一种降解产物，是 Ibuprofen 制剂中潜在的杂质。Ibuprofen 是一种 COX-1 和 COX-2 的抗炎抑制剂，IC50分别为 13 μM 和 370 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
YongFang, R., Xue, D., Pan, H., et al.Degradation of ibuprofen by a synergistic UV/Fe(III)/Oxone processChem. Eng. J.283,65-75(2016)
Vijay Kumar, R., Rao, V.U., Anil Kumar, N., et al.A novel, rapid, and validated stability-indicating UPLC method for the estimation of drotaverine hydrochloride and ibuprofen impurities in oral solid dosage formSci. Pharm.83(4),567-581(2015)
Méndez-Arriaga, F., Esplugas, S., and Giménez, J.Degradation of the emerging contaminant ibuprofen in water by photo-FentonWater Res.44(2),589-595(2010)
