24-Norursodeoxycholic acid
Cat. No.:YN480159
CAS No. :99697-24-2
产品名称: | 24-Norursodeoxycholic acid |
CAS No.: | 99697-24-2 |
Chemical Name: | (3α,5β,7β)-3,7-dihydroxy-24-norcholan-23-oic acid |
Synonyms: | nor-UDCA |
分子量: | 378.55 |
分子式: | C₂₃H₃₈O₄ |
SMILES: | C[C@H](CC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 24-norursodeoxycholic acid (norUDCA) 是侧链缩短的 UDCA 的 C23同系物,具有有效的抗胆汁淤积,抗炎和抗纤维化特性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Fickert, P., Wagner, M., Marschall, H.-U., et al.24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout miceGastroenterology130(2),465-481(2006)
Hofmann, A.F., Zakko, S.F., Lira, M., et al.Novel biotransformation and physiological properties of norursodeoxycholic acid in humansHepatology42(6),1391-1398(2005)