2-Thiouracil
Cat. No.:YN481820
产品名称: | 2-Thiouracil |
CAS No.: | 141-90-2 |
Chemical Name: | 2,3-dihydro-2-thioxo-4(1H)-pyrimidinone |
Synonyms: | 2-硫脲嘧啶; Thiouracil |
分子量: | 128.15 |
分子式: | C₄H₄N₂OS |
SMILES: | O=C(C=CN1)NC1=S |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 2-Thiouracil (Thiouracil) 是一种抗甲状腺化合物。2-Thiouracil 可作为一种高度特异性的黑色素瘤探测物。2-Thiouracil 是一种选择性的神经型一氧化氮合酶 (nNOS) 抑制剂,其Ki值为 20 μM。 |
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Itikawa, A., Kawada, J., and Ito, Y.Iodide goiter in the mouseEndocrinol. Jpn.14(4),333-341(1967)
Palumbo, A., Napolitano, A., De Martino, L., et al.Specific incorporation of 2-thiouracil into biological melaninsBiochim. Biophys. Acta1200(3),271-276(1994)
Palumbo, A., d'Ischia, M., and Cioffi, F.A.2-thiouracil is a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerisationFEBS Lett.485(2-3),109-112(2000)