SP-13786
Cat. No.：YN480081
CAS No. ：1448440-52-5
规格
价格(RMB)
库存
| 产品名称: | SP-13786 |
| CAS No.: | 1448440-52-5 |
| Chemical Name: | SP-13786; UAMC1110; |
| Synonyms: | (S)-N-[2-(2-氰基-4,4-二氟-1-吡咯烷基)-2-氧代乙基]喹啉-4-甲酰胺,UAMC-1110 |
| 分子量: | 344.32 |
| 分子式: | C₁₇H₁₄F₂N₄O₂ |
| SMILES: | O=C(C1=CC=NC2=CC=CC=C12)NCC(N3[C@H](C#N)CC(F)(F)C3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SP-13786 是高效和选择性的FAP抑制剂，IC50值为3.2 nM; 也可以抑制PREP，IC50值为1.8 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
De D., et al.: ACS Med. Chem., 10, 1173 (2019)
Simon, P., et al.: ACS Chem. Biol., 13, 3333 (2018)
De D., et al.: ACS Med. Chem. Lett., 10, 1173 (2019)
