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KR-33493

Cat. No.:YN480086

  • CAS No. :1021497-97-1

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    • 产品名称: KR-33493
      CAS No.: 1021497-97-1
      Chemical Name: 4-[[2-[(4-bromophenyl)thio]acetyl]amino]-1-(2-phenylethyl)-1H-pyrazole-3-carboxylic acid
      Synonyms:KR-33494
      分子量:460.34
      分子式:C₂₀H₁₈BrN₃O₃S
      SMILES:OC(C1=NN(CCC2=CC=CC=C2)C=C1NC(CSC3=CC=C(Br)C=C3)=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: KR-33493 是一个有效的 Fas 介导细胞死亡 (FAF1) 的抑制剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Park, H.S., Moon, B.S., Yoo, S.-E., et al.Assesment of potential protective effect on dopaminergic neuron by an Fas-associated factor 1 inhibitor treatment using [18F]FE-PE2I PET in a Parkinson's disease mouse modelJ. Nucl. Med.58(Suppl 1),13(2017)

      Yoo, S.-e., Yu, C., Jung, S., et al.Design and synthesis of fluorescent and biotin tagged probes for the study of molecular actions of FAF1 inhibitorBioorg. Med. Chem. Lett.26(4),1169-1172(2016)

      Jung, Y.S., Kim, E., Kim, N., et al.Aminopyrazole derivatives, process fo the preparation thereof, and composition for preventing or treating ischemic diseases containing the same,(2008)

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