AM-92016 hydrochloride
Cat. No.:YN480107
产品名称: | AM-92016 hydrochloride |
CAS No.: | 133229-11-5 |
Chemical Name: | N-[4-[3-[[2-(3,4-dichlorophenyl)ethyl]methylamino]-2-hydroxypropoxy]phenyl]-methanesulfonamide, monohydrochloride |
Synonyms: | AM-92016 HCl; AM 92016 HCl; AM92016 HCl; AM-92016 hydrochloride |
分子量: | 483.84 |
分子式: | C₁₉H₂₅Cl₃N₂O₄S |
SMILES: | CS(=O)(NC1=CC=C(OCC(O)CN(CCC2=CC=C(Cl)C(Cl)=C2)C)C=C1)=O.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AM-92016 hydrochloride 是整流钾电流 (IK) 的特异性阻断剂。 AM-92016 hydrochloride 延迟整流钾通道,使膜复极化,从而限制神经冲动的持续时间。 |
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Lei, M., and Brown, H.F.Inhibition by Compound II, a sotalol analogue, of delayed rectifier current (iK) in rabbit isolated sino-atrial node cellsNaunyn Schmiedebergs Arch Pharmacol.357(3),260-267(1998)
Hagerty, M.J., Wainwright, C.L., and Kane, K.A.The in-vivo cardiovascular effects of a putative class III anti-arrhythmic drug, AM 92016J. Pharm. Pharmacol.48(4),417-421(1996)