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AM-92016 hydrochloride

Cat. No.:YN480107

  • CAS No. :133229-11-5

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    • 产品名称: AM-92016 hydrochloride
      CAS No.: 133229-11-5
      Chemical Name: N-[4-[3-[[2-(3,4-dichlorophenyl)ethyl]methylamino]-2-hydroxypropoxy]phenyl]-methanesulfonamide, monohydrochloride
      Synonyms:AM-92016 HCl; AM 92016 HCl; AM92016 HCl; AM-92016 hydrochloride
      分子量:483.84
      分子式:C₁₉H₂₅Cl₃N₂O₄S
      SMILES:CS(=O)(NC1=CC=C(OCC(O)CN(CCC2=CC=C(Cl)C(Cl)=C2)C)C=C1)=O.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: AM-92016 hydrochloride 是整流钾电流 (IK) 的特异性阻断剂。 AM-92016 hydrochloride 延迟整流钾通道,使膜复极化,从而限制神经冲动的持续时间。
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    • Lei, M., and Brown, H.F.Inhibition by Compound II, a sotalol analogue, of delayed rectifier current (iK) in rabbit isolated sino-atrial node cellsNaunyn Schmiedebergs Arch Pharmacol.357(3),260-267(1998)

      Hagerty, M.J., Wainwright, C.L., and Kane, K.A.The in-vivo cardiovascular effects of a putative class III anti-arrhythmic drug, AM 92016J. Pharm. Pharmacol.48(4),417-421(1996)

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