MT-DADMe-ImmA
Cat. No.：YN480128
CAS No. ：653592-04-2
规格
价格(RMB)
库存
| 产品名称: | MT-DADMe-ImmA |
| CAS No.: | 653592-04-2 |
| Chemical Name: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(methylthio)methyl]-3-pyrrolidinol |
| Synonyms: | MTDIA; Methylthio-DADMe-Immucillin A |
| 分子量: | 293.39 |
| 分子式: | C₁₃H₁₉N₅OS |
| SMILES: | O[C@H]1CN(CC2=CNC3=C(N)N=CN=C32)C[C@@H]1CSC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MT-DADMe-ImmA是人5'-甲硫基腺苷磷酸化酶的抑制剂 (MTAP)，Ki值为90 pM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Evans, G.B., Furneaux, R.H., Lenz, D.H., et al.Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylaseJ. Med. Chem.48(14),4679-4689(2005)
Basu, I., Cordovano, G., Das, I., et al.A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancersJ. Biol. Chem.282(29),21477-21486(2007)
