Dihydrorhodamine 123
Cat. No.:YN480201
产品名称: | Dihydrorhodamine 123 |
CAS No.: | 109244-58-8 |
Chemical Name: | 2-(3,6-diamino-9H-xanthen-9-yl)-benzoic acid, methyl ester |
Synonyms: | DHR 123 |
分子量: | 346.38 |
分子式: | C₂₁H₁₈N₂O₃ |
SMILES: | O=C(OC)C1=CC=CC=C1C2C3=C(OC4=C2C=CC(N)=C4)C=C(N)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Dihydrorhodamine 123 (DHR 123) 是一种荧光探针 (λex=488 nm,λem=525 nm)。 |
IC50和靶点: | |
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Crow, J.P.Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen speciesNitric Oxide1(2),145-157(1997)
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Sies, H., Sharov, V.S., Klotz, L.O., et al.Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductaseJ. Biol. Chem.272,27812-27817(1997)
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Li, J., Baud, O., Volpe, J.J., et al.Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytesProc. Natl. Acad. Sci. USA102(28),9936-9941(2005)