NCT-503
Cat. No.:YN480216
产品名称: | NCT-503 |
CAS No.: | 1916571-90-8 |
Chemical Name: | N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-1-piperazinecarbothioamide |
Synonyms: | NCT 503 |
分子量: | 408.48 |
分子式: | C₂₀H₂₃F₃N₄S |
SMILES: | S=C(N1CCN(CC2=CC=C(C(F)(F)F)C=C2)CC1)NC3=NC(C)=CC(C)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NCT-503磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,IC50值为2.5 µM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Pacold, M.E., Brimacombe, K.R., Chan, S.H., et al.A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fateNat. Chem. Biol.12(6),452-458(2016)